Quantitative Determination of Ambroxol Hydrochloride in Syrups by RP-HPLC and UV Spectroscopy

RP-HPLC and UV Spectroscopy methods for the quantitation of ambroxol hydrochloride in syrups have been developed. Both methods were precise and accurate. A number of inactive ingredients present in the synthetic syrup did not interfere with the assay procedures. Although the methods had also good recovery for commercial syrups, but it was difficult to determine which method was more accurate than the other.