Highly Active Palladium Catalyst for the Sonogashira Coupling Reaction of Unreactive Aryl Chlorides

This communication reports on the β‐diketiminatophosphane palladium‐catalyzed copper‐free Sonogashira coupling of aryl chlorides with alkynes. A catalyst loading of 0.5 mol% is sufficient to achieve high performance under relatively mild reaction conditions. Furthermore, dialkynylbenzenes are efficiently prepared by one‐pot double Sonogashira couplings of aryl dichlorides.