|
|||||
|
|
Preparation of 5‐Membered Rings via Radical Addition‐ Translocation‐Cyclization (RATC) Processes Mediated by Diethyl Thiophosphites |
|
| Authors: | Christophe Lamarque,Florent Beaufils,Fabrice Dé nè s,Kurt Schenk,Philippe Renaud |
| Abstract: | A practical method for the formation of thiophosphonates bearing functionalized monocyclic, fused bicyclic and spirocyclic residues is presented. The procedure requires the easily available terminal alkynes as starting materials as well as commercially and readily available reagents such as diethyl thiophosphite. The experimental procedure consists of a one‐pot process without any slow addition of one of the reagents. |
| Keywords: | alkynes dialkyl phosphites dialkyl thiophosphites 1,5‐hydrogen transfer radical initiators radical reactions |