He-Ne激光照射对大鼠神经损伤后自残及神经再生的影响

本实验利用大鼠坐骨神经钳夹损伤模型 ,观察了氦氖 (He -Ne)激光照射 (A组 )、直流电针刺激器 (B组 )、对照组为 (C组 )对神经损伤后自残及神经再生的影响。结果 :( 1)术后 2 0d ,A组的右后足趾自残率为 13 % ,而B、C组分别为 46%、80 % ,A组的自残率显著低于其它各组(P <0 .0 0 1) ;( 2 )右侧屈肌反向阈 :当激光照射时光斑直径 0 .6cm ,功率密度为 3 5 .3 9mW/cm2 时 ,可引出短潜伏期 ( 4 5 -15 0ms)及长潜伏期 ( 12 5 5 2 5ms)传入纤维反应 ;( 3 )术后 2 0d脊神经节的标记细胞百分率分别为 11.1% (A组 )、5 .2 % (B组 )及 1.1% (C组 ) ;脊髓前角的标记细胞百分率分别为 16.6% (A组 )、8.1% (B组 )及 1.9% (C组 )。上述结果表明 :氦氖 (He -Ne)激光照射在抑制神经损伤后自残及促进周围神经再生等方面具有更显著的生理功效

Application of He-Ne laser radiation to reduce autotomy following sciatic nerve lesion in rats

This experiment uses the rat's sciatic nerve model and observes the irradiation of He-Ne laser (group A),electroacupuncture stimulation (group B) and contrait group C,the results show : <1> days after operation ,the percentage of autotomy in group A is 13%, and that of group B and group C are 46% and 80%. The percentage of group A is obviously lower than other groups (p<0.001).<2>hen light beam diameter is 0.6cm ,power density is 35.39mW/cm 2, we can get short concealing period (45-150ms ) and long concealing period (125-525ms) conduct light fiber reaction .<3>0days after operation , the percentage of the cell of organism is 16.6% (group A),8.1%(group B) and 1.9% (group C).The results show that the irradiation of He-Ne laser has more physiology ability in controling autotomy and nerve after injuries .