| 18F-FDG-PET/CT在弥漫大B细胞淋巴瘤中的分期诊断价值 |
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| 引用本文： | 朱海燕,李菲,王瑞民,刘长滨,汪菲菲,王书红,黄文荣,薄剑,靖彧,姚树林,尹大一,于力. 18F-FDG-PET/CT在弥漫大B细胞淋巴瘤中的分期诊断价值[J]. 压电与声光, 2010, 0(5) |
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| 作者姓名： | 朱海燕 李菲 王瑞民 刘长滨 汪菲菲 王书红 黄文荣 薄剑 靖彧 姚树林 尹大一 于力 |
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| 作者单位： | 解放军总医院血液科; |
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| 基金项目： | 首都医学科研发展基金资助项目(20072040)~~ |
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| 摘 要： | 目的旨在对比18F-FDG-PET/CT与CT在弥漫大B细胞淋巴瘤(DLBCL)中的分期诊断价值,分析DLBCL病灶的18F-FDG-PET/CT显像及分布特点。方法32例以淋巴结病理确诊的DLBCL患者,同时以18F-FDG-PET/CT及CT评价分期,18F-FDG-PET/CT及CT测量肿瘤病灶的部位、大小及SUVmax,计算与纵隔大血管主动脉弓血池SUVmax比值(T/MB)。结果18F-FDG-PET/CT及CT检测DLBCL病灶的一致率为70.6%,其敏感性分别为100%、75.8%,特异性分别为96%、4%,阳性预测值分别为99.7%、91.5%,阴性预测值分别为100%、1.2%,假阳性率分别为4%、96%,假阴性率分别为0、24.2%,准确率为99.7%、70.9%。结论18F-FDG-PET/CT对DLBCL检测的敏感性、特异性均明显好于CT,对多种结外病灶尤其是骨骼侵润的诊断较CT具有优越性,能够协助临床准确分期。DLBCL病灶的18F-FDG-PET/CT显像分布特点及T/MB值可供临床医生参考。
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| 关 键 词： | 18F-FDG PET/CT 淋巴瘤 大B细胞 弥漫性 肿瘤分期 |
Value of 18F-FDG positron emission tomography/computed tomography in staging of diffuse large B-cell lymphoma |
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| ZHU Hai-yan,LI Fei,WANG Rui-min,LIU Chang-bin,WANG Fei-fei,WANG Shu-hong,HUANG Wen-rong,BO Jian,JING Yu,YAO Shu-lin,YIN Da-yi,YU Li. Value of 18F-FDG positron emission tomography/computed tomography in staging of diffuse large B-cell lymphoma[J]. Piezoelectrics & Acoustooptics, 2010, 0(5) |
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| Authors: | ZHU Hai-yan LI Fei WANG Rui-min LIU Chang-bin WANG Fei-fei WANG Shu-hong HUANG Wen-rong BO Jian JING Yu YAO Shu-lin YIN Da-yi YU Li |
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| Affiliation: | ZHU Hai-yan,LI Fei,WANG Rui-min,LIU Chang-bin,WANG Fei-fei,WANG Shu-hong,HUANG Wen-rong,BO Jian,JING Yu,YAO Shu-lin,YIN Da-yi,YU Li Department of Hematology,Chinese PLA General Hospital,Beijing 100853,China |
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| Abstract: | Objective To evaluate the value of positron emission tomography/computed tomography(PET/CT) and CT in staging of diffuse large B-cell lymphoma(DLBCL).Methods Thirty-two patients with diffuse large B-cell non Hodgkin lymphoma were prospectively evaluated.All the patients who underwent a whole body 18F-FDG-PET/CT and CT(chest,abdomen and cavitas pelvis) were studied before therapy.The maximal standardized uptake value(SUVmax) of each single lesion and the SUVmax of mediastinal blood pool were measured and use... |
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| Keywords: | 18F-FDG PET/CT Lymphoma Large B-Cell Diffuse Neoplasm Staging |
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