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Production of 5-aminolevulinic acid by Propionibacterium acidipropionici TISTR442 |
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| Authors: | Kiatpapan Pornpimon Phonghatsabun Manthana Yamashita Mitsuo Murooka Yoshikatsu Panbangred Watanalai |
| Affiliation: | Rangsit University, Pathumthani 12000, Thailand. pornpimon@rsu.ac.th |
| Abstract: | Propionibacterium acidipropionici TISTR442 produced the highest amount of 5-aminolevulinic acid (ALA) when cultivated in medium supplemented with glycine at 18g/l. ALA production correlated with ALA synthase activity, whereas ALA dehydratase activity was maintained at a low level. ALA yield reached 405mg/l after prolonged cultivation for 1 month. |
| Keywords: | Propionibacterium acidipropionici 5-Aminolevulinic acid Glycine ALA synthase ALA dehydratase |
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