Electrospun salicylic acid/polyurethane composite nanofibers for biomedical applications |
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| Authors: | Bishweshwar Pant Mira Park Gunendra Prasad Ojha Dae-Up Kim Soo-Jin Park |
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| Affiliation: | 1. Department of Chemistry, Inha University, Incheon, Republic of Korea;2. Department of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju, Republic of Korea;3. Department of BIN Convergence Technology, Chonbuk National University, Jeonju, Republic of Korea;4. Korea Institute of Industrial Technology, Jeonju, South Korea |
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| Abstract: | Salicylic acid (SA)/polyurethane (PU) composite nanofiber mats were fabricated by introducing SA in PU solution during the electrospinning process. Cell viability assays showed that the as-prepared composite nanofibers had a good biocompatibility. Further, the composite mats showed good antibacterial performance against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacteria. Easy fabrication, good mechanical properties, good biocompatibility as well as the antibacterial activity of PU nanofibers containing SA indicated their significant promise for a variety of potential medical applications such as tissue engineering, wound healing, and drug delivery system. |
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| Keywords: | Antibacterial biomedical composite nanofibers electrospinning |
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