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Novel 3D electrospun polyamide scaffolds prepared by 3D printed collectors and their interaction with chondrocytes |
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| Authors: | Neda Shah Hosseini Nimet Bölgen Nabyl Khenoussi ?akir Necat Y?lmaz Derya Yetkin Amir Houshang Hekmati |
| Affiliation: | 1. Department of Textile, Laboratoire de Physique et Mécanique Textiles EAC 7189 CNRS–UHA, Mulhouse, France;2. Department of Chemical Engineering, Faculty of Engineering, Mersin University, Mersin, Turkey;3. Department of Histology and Embryology, Faculty of Medicine, Mersin University, Mersin, Turkey;4. Department of Textile Engineering, Faculty of Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran |
| Abstract: | Electrospinning is significantly one of the simple and versatile methods for producing micro- and nanofibrous scaffolds. Its assembly can be modified in different ways to combine material properties with different morphological structures for biomedical applications. In this process, collector design plays an important role to determine the nanofiber orientation in electrospun nanoweb. In this work, 3D patterned scaffolds were produced by electrospinning of polyamide-66 solution on different 3D collectors that have been obtained. The aim of this work is to investigate the attachment of the chondrocyte cells on the prepared electrospun scaffolds that have different types of nanofiber orientations that could be used in tissue engineering applications. |
| Keywords: | 3D printer cell culture chondrocytes electrospinning nanofibers patterned collectors polyamide-66 scaffold tissue engineering |