| 5，7-二甲基-1，2，4-三唑并[1，5-a]嘧啶-2-羧（磺）酸酯类化合物的合成及生物活性 |
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| 引用本文： | 郑敏,沈德隆,金建锋,周红芳.5，7-二甲基-1，2，4-三唑并[1，5-a]嘧啶-2-羧（磺）酸酯类化合物的合成及生物活性[J].浙江化工,2009,40(5):1-4. |
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| 作者姓名： | 郑敏 沈德隆 金建锋 周红芳 |
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| 作者单位： | 浙江工业大学,农药研究所,浙江,杭州,310014 |
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| 摘 要： | 以2-羟基-5，7-二甲基-1，2，4-三唑并1，5-a]嘧啶为原料，与杂环和苯环取代的（磺）酰氯化合物进行酯化反应，制备得到三唑并嘧啶类羧（磺）酸酯类化合物ZJUT-7。化合物ZJUT-7经^1H NMR和MS确定，并对其进行了初步生物活性测试。
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| 关 键 词： | 2-羟基-5 7-二甲基-1 2 4-三唑并【1 5-a】嘧啶 酯化反应 生物活性 |
Synthesis and Bioactivity of Triazole-(1,5-a)-pyrimidin-2-yl-5,7-dimethyl Carboxylic Acid Esters and Sulphonic Acid Esters |
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| ZHENG Min,SHEN De-long,JIN Jian-feng,ZHOU Hong-fang.Synthesis and Bioactivity of Triazole-(1,5-a)-pyrimidin-2-yl-5,7-dimethyl Carboxylic Acid Esters and Sulphonic Acid Esters[J].Zhejiang Chemical Industry,2009,40(5):1-4. |
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| Authors: | ZHENG Min SHEN De-long JIN Jian-feng ZHOU Hong-fang |
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| Affiliation: | (Pesticide Research Institute, Zhejiang University of Technology, Hangzhou 310014, China) |
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| Abstract: | Triazole-（1,5-a）-pyrimidin-2-yl-5,7-dimethyl carboxylic acid esters and sulfonic acid esters Z JUT 1-7 were synthesized by esterification of heterocyclic compounds and aromatic compounds with triazole-2- hydroxy-5,7-dimethyl-（1,5-a）-pyrimidine. Their structures were confirmed by ^1H NMR and MS, and their preliminary biological activity were tested. |
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| Keywords: | triazole-2-hydroxy-5 7-dimethyl-（1 5-a）-pyrimidine esterification action biological activity |
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