Gastrointestinal Transit Time:— An in Vitro Analysis of the Various Parameters Controlling the Critical Flow Velocity of Particles in a Horizontal Tube

Abstract

The factors which affect the critical flow velocity (V_c) of particles of barium sulphate, bismuth subcarbonate, kaolin, sulphadiazine and latex particles has been determined in a horizontal tube. These factors were particle size, particle density, fluid viscosity and tube diameter. V_c was found to increase with increasing particle diameter, particle density and tube diameter but decreases as viscosity of the flowing fluid. The results obtained were found to fit the models of Wicks, Durand and Wasp for the flow conditions of settled beds.