对甲苯磺酸催化合成季戊四醇双缩醛或酮

以季戊四醇和醛（酮）为原料,对甲苯磺酸为催化剂,合成了季戊四醇双缩醛（酮）化合物。探索了物料配比、催化剂种类及用量、带水剂等反应条件对产率的影响,确定了最佳工艺条件。实验结果表明：物料配比n（季戊四醇）∶n（醛或酮）为1.0∶2.2,催化剂为对甲苯磺酸,用量为0.4 g,带水剂为苯,用量30 mL。在最佳工艺条件下所制得的产品为白色粉末状固体,所得季戊四醇双缩醛或酮的产率在83%以上。通过元素分析、红外谱图、熔点和1HNMR对产品进行了物性和结构表征。

Synthesis of Pentaerythritol Diacetals and Pentaerythritol Diketals Catalyzed by P-toluene Sulphonic Acid

By using paratoluenesulfonic acid as catalyst, pentaerythritol diacetal and Pentaerythritol diketal are synthesized from pentaerythritol, aldehyde and ketone. The influences of material ratio, the catalyst species and the water-carrying agent on the yield were investigated. The optimal condition was obtained as follows, the mole ratio between pentaerythritol and benzaldehyde is 1.0 - 2.2, the catalyst is paratoluenesulfonic acid, the quantity of catalyst is O. 4 g, and the water-carrying agent is benzol. The product was solid white powder under the optimal reaction con ditions, whose melting point was 157-158℃ and the yield was about 92.5%. Bisides, the prod uet was characterized by elemental analysis, IR, melting point determination and ^1 HNMR.