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麦麸酶解产物对糖尿病大鼠氧化应激损伤的保护作用
引用本文:焦霞,陈静,欧仕益,周红锋. 麦麸酶解产物对糖尿病大鼠氧化应激损伤的保护作用[J]. 食品与机械, 2006, 22(2): 27-29
作者姓名:焦霞  陈静  欧仕益  周红锋
作者单位:1. 暨南大学食品科学与工程系,广东,广州,510632
2. 暨南大学医学院营养教研室,广东,广州,510632
基金项目:广东省广州市科技攻关项目
摘    要:用四氧嘧啶制备SD大鼠糖尿病模型,以麦麸酶解产物(EHWB)为受试物,测定各实验组大鼠血糖,血清、肝脏和睾丸总抗氧化能力(T-AOC)及超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSHPx)和黄嘌呤氧化酶(XOD)活性及丙二醛(MDA)含量。结果表明,与糖尿病组相比,EHWB治疗组大鼠血糖明显降低,TAOC能力升高,GSHPx和SOD活性增强,XOD活性降低,MDA含量明显降低。表明EHWB具有显著降血糖和提高糖尿病大鼠抗氧化能力的作用。

关 键 词:麦麸酶解产物  糖尿病  抗氧化
收稿时间:2005-11-27
修稿时间:2005-11-27

Protective effects of enzymes-hydrolyzed wheat bran on diabtes rats oxidative damage
JIAO Xia,CHEN Jing,OU Shi-yi,ZHOU Hong-feng. Protective effects of enzymes-hydrolyzed wheat bran on diabtes rats oxidative damage[J]. Food and Machinery, 2006, 22(2): 27-29
Authors:JIAO Xia  CHEN Jing  OU Shi-yi  ZHOU Hong-feng
Affiliation:1. Department of Food Science and Engineering, Jinan University, Guangzhou , Guangdong 510632, China ; 2. The Division of Nutrition Science of the College of Medicine, Jinan University, Guangzhou ,Guangdong 510632,China
Abstract:Diabetes mellitus was induced by Alloxan injection and enzyme-hydrolysed wheat bran (EHWB) was used to test its effect on antioxidation capacity. The EHWB was given intragastrically (i.g.). The level of blood glucose, total antioxidative capacity (T-AOC), the activity of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px),xanthine oxidase (XOD) and the content of malondiadehyde (MDA) were detected respectively in serum, liver and testis of rats. The results showed that EHWB significantly decreased the level of blood glucose and increased the level of T-AOC, as well as the activity of GSH-Px and SOD, and decreased the activity of XOD and the content of MDA.
Keywords:Enzymes-hydrolyzed wheat bran  Diabetes mellitus  Antioxidant
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