Encapsulated islet cells: the role of direct and indirect presentation and the relevance to xenotransplantation and autoimmune recurrence |
| |
Authors: | DW Gray |
| |
Affiliation: | Nuffield Department of Surgery, John Radcliffe Hospital, Oxford, UK. |
| |
Abstract: | Immuno-isolation of islet tissue for the purpose of curing diabetes without immunosuppression is an attractive concept that has been extensively investigated over the last 20 years. Rather than give a detailed review of the past and present history of the immuno-isolation or encapsulation approach for islet transplantation, this paper will examine the concepts behind encapsulation, concentrating on the immune mechanisms involved. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|