Abstract: | Isolated nephrons from premetamorphic lamprey larvae and adult animals were obtained using microdissection and kidney collagenase treatment methods. Significant differences in the architectonics of kidney tubules were found in larvae as compared with adults. The position of larval kidney was cranial while that in adult lampreys was caudal. The absence of nephron loop was noted in larval kidney. Distal and proximal tubules were shifted one from another in mediolateral direction. Distal tubule was significantly larger than proximal one. Mesonephric duct was located laterally near the glomus. Kidney tubules morphogenesis and nephron population number increase was observed at premetamorphic stage of larval kidney development. |