|
|||||
|
|
N-Alkylation During the Removal of a Carbamate-Type Protecting Group |
|
| Authors: | T Sheradsky G Salemnick M Frankel |
| Abstract: | Acidolysis of 2-(p-biphenylyl)isopropyl N-(5-nitro-2-pyridyloxy)carbamate (IV) resulted in loss of carbon dioxide and formation of N-2-(p-biphenylyl)isopropyl-O-(5-nitro-2-pyridyl) hydroxylamine (V). The mechanism of this unusual reaction is discussed. |
| Keywords: | |