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Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of the Drug Delivery Effect by Exocytosis Inhibition
Authors:Rolando E Yanes  Derrick Tarn  Angela A Hwang  Daniel P Ferris  Sean P Sherman  Courtney R Thomas  Jie Lu  April D Pyle  Jeffrey I Zink  Fuyuhiko Tamanoi
Affiliation:1. Department of Microbiology, Immunology and Molecular Genetics, California NanoSystems Institute, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, 405 Hilgard Avenue, Los Angeles, CA 90095, USA, Tel: (+1)‐310‐206‐7318, Fax: (+1)310‐206‐5231;2. Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA;3. Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA;4. Eli and Edythe Broad Center of Regenerative, Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA
Abstract:
Keywords:mesoporous silica nanoparticles  lysosomal exocytosis  drug delivery  exocytosis inhibition
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