Oxygen‐releasing biomaterials for tissue engineering |
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| Authors: | Gulden Camci‐Unal Neslihan Alemdar Nasim Annabi Ali Khademhosseini |
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| Affiliation: | 1. Center for Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, , Cambridge, MA, 02139 USA;2. Harvard‐MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, , Cambridge, MA, 02139 USA;3. Wyss Institute for Biologically Inspired Engineering, Harvard University, , Boston, MA, 02115 USA |
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| Abstract: | Due to the increasing demand to generate thick and vascularized tissue‐engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen‐releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue constructs. Biomaterials containing oxygen‐releasing molecules can be fabricated in various forms, such as hybrid thin films, microparticles or three dimensional scaffolds. In this perspective, we summarize various oxygen‐releasing reagents and their potential applications in regenerative engineering. Moreover, we review the main approaches for fabricating oxygen‐releasing biomaterials for a range of tissue engineering applications. © 2013 Society of Chemical Industry |
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| Keywords: | oxygen‐releasing biomaterials peroxides cell survival tissue engineering |
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