Lewis酸离子液体催化合成对甲氧基苯乙酮

合成并表征了Lewis酸离子液体,用于催化合成对甲氧基苯乙酮。通过考察各种离子液体的催化活性及重复使用性能,选定Lewis酸离子液体[Bmim]Cl-AlCl3为催化剂,研究了醇酸摩尔比、反应时间、反应温度等因素对酰化反应的影响,得到其较佳工艺条件:醇酸摩尔比1∶1.5,反应温度60℃,反应时间6 h。此条件下,酯化率达到78.8%。分离后的离子液体经真空干燥后重复使用5次,催化活性基本不变。

Synthesis of p-acetylanisole catalyzed by Lewis acidic ionic liquids

Lewis acidic ionic liquids were synthesized, characterized, and used in p-acetylanisole synthesis as catalysts. According to the study of catalytic activity and the reusability of various ionic liquids, [Bmim]Cl-AlCl_3 was chosen to synthesize p-acetylanisole as catalyst. The effects of the reaction conditions on the reaction results such as molar ratio of anisole to acetic anhydride, reaction time, reaction temperature were examined. The optimal conditions were obtained as follows: n (anisole): n (acetic anhydride)=1: 1.5, 60 ℃, 6 h. Under the optimal reaction conditions, the conversion can be 78.8%. The ionic liquids can be repeatedly used for five times after distillation and vacuum drying without considerable loss of activity.