Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked polyethylene in artificial hip joints |
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| Authors: | Masayuki Kyomoto Toru Moro Tomohiro Konno Hiroaki Takadama Hiroshi Kawaguchi Yoshio Takatori Kozo Nakamura Noboru Yamawaki Kazuhiko Ishihara |
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| Affiliation: | (1) Research and Development Corporate Division, Japan Medical Materials Corporation, Uemura Nissei Bldg. 9F, 3-3-31 Miyahara, Yodogawa-ku, Osaka 532-0003, Japan;(2) Department of Orthopaedic Surgery, School of Medicine, The University of Tokyo, Tokyo, Japan;(3) Department of Materials Engineering, School of Engineering and Center for NanoBio Integration, The University of Tokyo, Tokyo, Japan;(4) Materials Research and Development Laboratory, Japan Fine Ceramics Center, Atsuta-ku, Nagoya, Japan |
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| Abstract: | Osteolysis caused by wear particles from polyethylene in the artificial hip joints is a serious issue. We have used photo-induced
radical graft polymerization to graft 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer onto the surface of cross-linked
polyethylene (CLPE-g-MPC) in order to reduce friction and wear at the bearing surface of the joint. The physical and mechanical properties of CLPE
and CLPE-g-MPC were not significantly different, expect that the friction coefficient of untreated CLPE cups was 0.0075, compared with
0.0009 for CLPE-g-MPC cup, an 88% reduction. After 3.0 × 106 cycles in the hip joint simulator test, we could not observe any wear of CLPE-g-MPC cups. We concluded that the advantage of photo-induced radical graft polymerization technique was that the grafted MPC
polymer gave a high lubricity only on the surface and has no effect on the bulk properties of the CLPE substrate. |
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