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Understanding the Effect of Tamarind Gum Proportion on the Properties of Tamarind Gum-Based Hydroethanolic Physical Hydrogels |
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| Authors: | Suprio R. Paul Suraj K. Nayak Yamini Yogalakshmi Vinay K. Singh Archana Rath Indranil Banerjee |
| Affiliation: | 1. Amity Institute of Biotechnology, Amity University, Noida, NCR, India;2. Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, India |
| Abstract: | The present study reports the analysis of properties of tamarind gum-based hydroethanolic physical hydrogels. The extent of hydrogen bonding in hydrogels decreased with an increase in tamarind gum content. The hydrogel with the highest tamarind gum content was found to be highly stable in terms of mechanical properties. There was a decrease in the resistive component of the hydrogels with an increase in tamarind gum content. The drug release from the hydrogels increased with an increase in the tamarind gum content. The antimicrobial activity of the drug-loaded hydrogels against Escherichia coli was excellent. |
| Keywords: | Antimicrobial drug release hydrogel tamarind gum viscoelastic |