| 益生乳酸菌Lactobacillus casei Zhang从基础研究到产业化开发 |
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| 引用本文： | 张和平. 益生乳酸菌Lactobacillus casei Zhang从基础研究到产业化开发[J]. 中国乳品工业, 2011, 39(10) |
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| 作者姓名： | 张和平 |
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| 作者单位： | 内蒙古农业大学乳制品加工研究室,呼和浩特,010018 |
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| 基金项目： | 农业部现代农业产业技术体系建设项目(nycytx-0501); 国家高技术研究发展计划(2011AA100901,2011AA100902); 国家杰出青年科学基金(31025019); 973计划前期研究专项(2010CB134502); 教育部创新团队发展计划(IRT0967); “十一五”国家科技支撑计划重点项目(2009BADC1B01) |
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| 摘 要： | 2001年-2009年,内蒙古农业大学乳品生物技术与工程教育部重点实验室从采集自中国西部7个省市及蒙古国14个省市不同少数民族地区951份自然发酵乳制品等样品中分离鉴定出3 388株乳酸菌,建立了中国首个原创性乳酸菌菌种资源库;从菌种库中分离自传统发酵酸马奶(koumiss)的243株乳杆菌中筛选获得1株性能优良的乳酸菌—Lactobacillus casei Zhang(L.casei Zhang)。采用5种动物模型和人体试验进行了功能评价,并利用基因组学和蛋白质组学研究技术对L.casei Zhang益生分子机制进行了深入剖析。经过多年系统的基础研究,自主解决了其产业化的关键技术问题,包括其直投式发酵剂、发酵乳制品和发酵豆乳益生菌饮料的研发并实现了产业化。
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| 关 键 词： | 益生菌Lactobacillus casei Zhang 基础研究 产业化 |
Probitotic Lactobacillus casei Zhang from basic research to industrialization |
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| ZHANG He-ping. Probitotic Lactobacillus casei Zhang from basic research to industrialization[J]. China Dairy Industry, 2011, 39(10) |
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| Authors: | ZHANG He-ping |
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| Affiliation: | ZHANG He-ping(Key Laboratory of Dairy Biotechnology and Engineering,Education Ministry of China,Dairy Processing Laboratory of National Dairy Industry and Technology System,Inner Mongolia Agricultural University,Hohhot 010018,China) |
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| Abstract: | During 2001-2009,we have isolated,identified and collected 3,388 strains of lactic acid bacteria from 951 naturally fermented dairy products(including fermented cow milk,mare milk,goat milk,camel milk and yak milk) in Inner Mongolia,Xinjiang,Qinghai,Tibet,Yunnan,Ganshu and Sichuan of China and 17 provinces of Mongolia,and established the first LAB Collection Center(LABCC) with self-owned intellectual property in China.From 243 strains of lactobaclli isolated from naturally fermented mare milk(koumiss) colle... |
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| Keywords: | Probiotic Lactobacillus casei Zhang Basic research Industrialization |
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