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Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells
Authors:Marie Kalbacova  Antonin Broz  Jing Kong  Martin Kalbac
Affiliation:aInstitute of Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University in Prague, Ke Karlovu 2, 12808 Prague 2, Czech Republic;bDepartment of Electrical Engineering and Computer Science, MIT, Cambridge, MA 02139, USA;cJ. Heyrovský Institute of Physical Chemistry v.v.i, Academy of Sciences of the Czech Republic, Dolejškova 3, 18223 Prague 8, Czech Republic;dPalacky University, Department of Physical Chemistry, Olomouc 77146, Czech Republic
Abstract:The biocompatibility of large single layer graphene produced by chemical vapour deposition was investigated using human osteoblasts and mesenchymal stromal cells. The study was focused on cellular adhesion, morphology and the ability to proliferate on graphene substrates. It was found that both of the cell types which were tested adhered and proliferated better when cultured on graphene films than on a SiO2 substrate.
Keywords:
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