Technical note: Modeling primate occlusal topography using geographic information systems technology |
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Authors: | LF Zuccotti MD Williamson WF Limp PS Ungar |
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Affiliation: | Department of Cell Biology, Human Genome Sciences, Inc., Rockville, Maryland, 20850, USA. KamvLeung@hgsi.com |
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Abstract: | We studied the effects of FGF-13 and FGF-2 on human lung fibroblasts, dermal microvascular endothelial cells, and aortic smooth muscle cells. FGF-13 induced cell growth of lung fibroblasts and aortic smooth muscle cells but had no effect on dermal vascular endothelial cells. FGF-2 induced cell growth in all the three cell types. FGF-13 and FGF-2 had little effect on IL-6 production by lung fibroblasts and aortic smooth muscle cells and substantially enhanced that induced by IL-1alpha. In contrast, FGF-13 and FGF-2 had little effect on IL-6 production by dermal vascular endothelial cells, either alone or in synergy with IL-1alpha. |
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