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Fast automated NMR spectroscopy of short-lived biological samples
Authors:Tikole Suhas  Jaravine Victor  Rogov Vladimir V  Rozenknop Alexis  Schmöe Kerstin  Löhr Frank  Dötsch Volker  Güntert Peter
Affiliation:Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance, Goethe University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt am Main, Germany.
Abstract:Faster than death: NMR techniques that make use of nonlinear sampling and hyperdimensional processing enable the recording of complete NMR data sets for the automated assignment of the backbone and side-chain resonances of short-lived protein samples of cell lysates.
Keywords:cell lysates  hyperdimensional processing  NMR spectroscopy  peak‐picking  proteins  resonance assignment
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