Propranolol hydrochloride degradation using La@TiO2 functionalized with CMCD |
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Affiliation: | 1. Post-Graduate Program in Technology and Innovation Management, Community University of Chapecó Region, Chapecó, 89809-900, Brazil;2. Department of Chemical Engineering, Community University of Chapecó Region, Chapecó, 89809-900, Brazil;3. Laboratory of Materials and Scientific Computing (LabMAC), Department of Chemical and Food Engineering, Federal University of Santa Catarina, Florianópolis, 88040-900, Brazil |
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Abstract: | Propranolol hydrochloride can be considered a persistent and bioaccumulative pharmaceutical in the environment. This drug and its by-products are potentially toxic and have adverse effects, since these compounds have been associated with endocrine-disrupting effects, reproductive deficiencies, embryo abnormalities and pericardial oedema. TiO2–La 0.05%–carboxymethyl-β-cyclodextrin (CMCD) nanoparticles were successfully prepared by a simple two-step method, which consists of sonification and functionalization. The characterization analyses reveal that lanthanum is dispersed on the semiconductor surface, probably forming Ti–O–La bonds, which can induce oxygen vacancies and surface defects that effectively restrain the recombination of photogenerated electron/holes pairs. The efficiency of TiO2–La 0.05%–CMCD samples in degradation of propranolol under UV-light irradiation is higher than that of pristine TiO2 within 20 min reaction, probably due to complex formation between the β-blocker and the oligosaccharide, which allows us to propose a photocatalytic mechanism based on the formation of intermediates and competition of these compounds to the radicals and CMCD cavities. |
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Keywords: | Lanthanum CMCD Propranolol Photocatalysis Functionalization |
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