基于氧化石墨烯的表面增强拉曼光谱技术在食品污染物检测中的应用

表面增强拉曼光谱(surface enhanced Raman spectroscopy, SERS)通过吸附表面的目标分子来增强拉曼散射，能够以高灵敏度、高特异性和高选择性检测目标分子，已成为快速检测食品污染物的一种常见技术。SERS技术的发展很大程度上依赖于SERS基底的构建与发展，常用的SERS基底材料主要为贵金属(Au、Ag和Cu)，并且氧化石墨烯(graphene oxide, GO)也是一种具有拉曼活性的探针分子，可通过与贵金属的协同作用来增强表面增强拉曼光谱的信号，此外GO材料本身的自清洁性、稳定性和优越的分子吸附特性等，使得基于GO的SERS生物传感器的开发成为研究的热点。本文系统地介绍了GO SERS基底材料，综述了其在多种农药、霉菌毒素和非法添加剂等食品污染物检测中的研究应用，并对其应用进行总结和前景展望。本文旨在为研究人员提供更多GO SERS传感器的相关知识和应用前景。

Application of surface enhanced Raman spectroscopy based on graphene oxide in the detection of food contaminants

Surface enhanced Raman spectroscopy (SERS) enhances Raman scattering by adsorbing target molecules on the surface, which can detect target molecules with high sensitivity, high specificity and high selectivity. It has become a common technique for rapid detection of food contaminants. The development of SERS technology largely depends on the construction and development of SERS substrate. The commonly used SERS substrate materials are mainly precious metals (Au, Ag and Cu), and graphene oxide (GO) is also a probe molecule with Raman activity. The signal of SERS can be enhanced through the synergistic interaction with precious metals. In addition, the self-cleaning, stability and superior molecular adsorption characteristics of GO materials make the development of SERS biosensors based on GO become a research hotspot. This paper systematically introduced GO SERS substrate material, reviewed its research and application in the detection of various pesticides, mycotoxins and illegal additives and other food pollutants were reviewed, and summarized its application and prospect. This paper aims to provide researchers with more knowledge and application prospects of GO SERS sensors.