| 无机纳米基因载体的研究进展 |
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| 引用本文： | 黄苏萍,朱军,孙虹,周科朝. 无机纳米基因载体的研究进展[J]. 材料导报, 2010, 24(15) |
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| 作者姓名： | 黄苏萍 朱军 孙虹 周科朝 |
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| 作者单位： | 中南大学粉末冶金国家重点实验室,长沙,410083;中南大学湘雅三医院,长沙,410083;中南大学粉末冶金国家重点实验室,长沙,410083;中南大学湘雅三医院,长沙,410083 |
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| 基金项目： | 中国博士后基金,湖南省自然科学基金 |
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| 摘 要： | 介绍了无机纳米基因载体的特性及其负载与转染机理,主要综述了二氧化硅、磷酸钙、碳纳米管、氧化铁、量子点和层状双氢氧化合物等的研究进展,分析了其研究现状,并提出了进一步的研究方向及发展趋势.
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| 关 键 词： | 基因治疗 基因载体 无机纳米颗粒 |
Research Progress of Inorganic Nanoparticle as Gene Vector |
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| HUANG Suping,ZHU Jun,SUN Hong,ZHOU Kechao. Research Progress of Inorganic Nanoparticle as Gene Vector[J]. Materials Review, 2010, 24(15) |
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| Authors: | HUANG Suping ZHU Jun SUN Hong ZHOU Kechao |
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| Affiliation: | HUANG Suping1,2,ZHU Jun1,SUN Hong2,ZHOU Kechao1(1 State Key Lab of Powder Metallurgy,Central South University,Changsha 410083,2 3rd Xiangya Hospital,Changsha 410083) |
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| Abstract: | This article describes the characteristics of inorganic nanoparticle as gene vector and its mechanism of load and transfection,and reviews the recent researches on the silica,calcium phosphate,carbon nanotubes,iron oxide,quantum dots,and layered double hydroxide compounds,which also analyzes the research situation and proposes direction for further research and development trend on the inorganic nanoparticles as gene vector. |
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| Keywords: | gene therapy gene vector inorganic nanoparticles |
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