American cutaneous leishmaniasis in a military training center located in Zona da Mata, Pernambuco, Brazil |
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Authors: | SP Brand?o-Filho ME de Brito CA Martins IB Sommer HF Valen?a FA Almeida J Gomes |
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Affiliation: | Institute of Inherited Metabolic Disorders, 1st Faculty of Medicine and University Hospital, Charles University, Prague, Czech Republic. |
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Abstract: | In a case of infantile mucolipidosis type II (I-cell disease), storage was identified at autopsy in serous-type secretory cells in exocrine pancreas, in the tracheal and sublingual salivary glands and in the chief (zymogenic) cells of the gastric oxyntic glands, suggesting a systemic involvement of this type of secretory cells. The content of specific secretory granules was inversely proportional to the intensity of the storage process. The mucus-producing cells were not affected. The serous glandular system is a novel storage site in I-cell disease. Review of archival material in three further cases confirmed the findings. |
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