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A Novel Three-Dimensional Hydrogel-Based Microarray Platform
Authors:Douglas Gurevitch    X. Fan Dong    Tony J. Pircher    Sandra S. Matsumoto    Pat Roycroft    Pavel Tsinberg    Yehudit H. Falcovitz  Soonkap Hahn
Abstract:Three dimensional (3D) microarrays utilizing hydrogel matrixes are becoming increasingly attractive as a desired format for bio-analysis. These materials offer significant advantages as a scaffolding for capture agents over more conventional two dimensional (2D) printed formats in both captures per site and the ability to provide an environment more closely resembling that of a free solution. Biocept has developed a flexible three dimensional polyethylene glycol (PEG) polymer based platform suitable for a variety of biological assays. This novel approach is simple, biocompatible and provides a high degree of reproducibility and very low variability in the final array.
Keywords:Author Keywords: MICROARRAY   HYDROGEL   DNA-ARRAY   PROTEIN-ARRAY
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