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Effects of probiotic yoghurt on symptoms and intestinal microbiota in patients with irritable bowel syndrome |
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| Authors: | Jin Lee Sungsue Rheem Bohyun Yun Youngjun Ahn Jaeyeon Joung Suk Jun Lee Sejong Oh Taehoon Chun Insoo Rheem Hyun Soo Yea Kwang Sei Lim Jae Myung Cha Saehun Kim |
| Affiliation: | 1. Division of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea University, , Seoul, 136‐701 South Korea;2. Department of Informational Statistics, College of Sciences and Technology, Korea University, , Jochiwon, 339‐700 South Korea;3. Division of Animal Science, Chonnam National University, , Gwangju, 500‐757 South Korea;4. Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, , Seoul, 136‐701 South Korea;5. Department of Laboratory Medicine, College of Medicine, Dankook University, , Cheonan, 330‐715 South Korea;6. R&D Center, Maeil Dairies Co, , Gyeonggi‐do, 451‐861 South Korea;7. Department of Internal Medicine, College of Medicine, Kyung Hee University, , Seoul, 134‐727 South Korea |
| Abstract: | The aim of the present study was to investigate the efficacy of probiotic yoghurt Lactobacillus rhamnosus GG (LGG) in the treatment of Irritable bowel syndrome (IBS). Eighty‐three IBS patients yielded data to be analysed from this 9‐week, placebo‐controlled, double‐blind and randomized trial. The patients consumed either a LGG‐containing probiotic yoghurt (treatment group; n = 44) or a placebo (n = 39) twice daily for 6 weeks. The results indicate that this probiotic yoghurt was effective in alleviating some IBS symptoms and resulted in slight changes in certain gut microbiota. Probiotic yoghurt may represent a treatment for some gastrointestinal disorders. |
| Keywords: | Probiotic yoghurt Irritable bowel syndrome Faecal microbiota DGGE IBS symptom |