Sesquiterpenoids of the drimane class from a sponge of the genus Dysidea |
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Authors: | VJ Paul Y Seo KW Cho JR Rho J Shin PR Bergquist |
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Affiliation: | Marine Laboratory, University of Guam, Korea. |
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Abstract: | Ten sesquiterpenoids, including seven new ones, have been isolated from an undescribed sponge of the genus Dysidea. Compounds 1-8 are sesquiterpenoids of the drimane class, while 9 and 10 are 12-norsesquiterpenoids of the same structural class. The structures of novel compounds have been determined by combined spectroscopic methods. These compounds exhibited moderate antimicrobial and enzyme inhibitory (Na+/K(+)-ATPase and PLA2) activities. |
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