| ^59Fe,^60Co在大鼠体内诱发细胞遗传学效应的研究 |
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| 引用本文： | 张鸿源,王德恒.^59Fe,^60Co在大鼠体内诱发细胞遗传学效应的研究[J].辐射研究与辐射工艺学报,1990,8(2):95-99. |
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| 作者姓名： | 张鸿源 王德恒 |
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| 作者单位： | 海军医学研究所 上海
(张鸿源，王德恒，田伍训，温泉法，蔡平，王兰金，赵山银，胡跃新，李勇)，海军医学研究所 上海(刘同水) |
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| 摘 要： |
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| 关 键 词： | 辐射 大鼠 细胞 遗传效应 诱发 |
RADIATION-CYTOGENETIC EFFECTS OF RADIOACTIVE NUCLIDES ~(59)F,~(60 CO ON WISTAR RATS |
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| Zhang Hongyuan,Wang Deheng,Taen Wuxun,Wen Quanfa,Cai Ping,Wang Lanjin,Zhao Shanyin,Hu yuexin,Li yong,Liu Tongshui Institute of Naval Medicine,Shanghai.RADIATION-CYTOGENETIC EFFECTS OF RADIOACTIVE NUCLIDES ~(59)F,~(60 CO ON WISTAR RATS[J].Journal of Radiation Research and Radiation Processing,1990,8(2):95-99. |
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| Authors: | Zhang Hongyuan Wang Deheng Taen Wuxun Wen Quanfa Cai Ping Wang Lanjin Zhao Shanyin Hu yuexin Li yong Liu Tongshui Institute of Naval Medicine Shanghai |
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| Abstract: | The radiactive nuclides were administered by gastric probe to ratswith average activity 1. 64, 1. 48, 1. 04, MBq/rat of ~(59)Fe and 2. 08, 2. 12, 1. 81MBq/rat of ~(80)Co respectively for young, adult and old groups. The cumulatedinternal doses to total body and R. M were calculated on the basis of radioactivitymeasurements on total body and organs. The results showed the chromosomalaberration yields of bone marrow cells and blood lymphocytes in experimental rats ofvarious age-groups were higher than that of controls, the differences between the ex-perimental and control groups were statistically significant at most dose points, mo-reover, the linear relationships existed between R. M cumulated doses and chromosomeacentrics of bone marrow cells in old rats exposed to ~(69)Fe and ~(60)Co, the SCE inciden-ces in lymphocytes of rats of various age-groups incorporated with ~(59)Fe and ~(60)Co didnot greatly changed. |
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| Keywords: | ~(59)Fe ~(60)Co Radiation-Cytogenetic effect Chromosomal aberration SCE |
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