Non-rigid registration using gradient of self-similarity response |
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Authors: | James L Huang Jeffrey J Rodriguez |
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Affiliation: | Dept. of Electrical and Computer Engineering, The University of Arizona, 1230 E. Speedway Blvd., Tucson, AZ 85721-0104, USA |
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Abstract: | Locally affine transformation with globally elastic interpolation is a common strategy for non-rigid registration. Current techniques improve the registration accuracy by only processing the sub-images that contain well-defined structures quantified by Moran's spatial correlation. As an indicator, Moran's metric successfully excludes noisy structures that result in misleading global optimum in terms of similarity. However, some well-defined structures with intensity only varying in one direction may also cause mis-registration. In this paper, we propose a new metric based on the response of a similarity function to quantify the ability of being correctly registered for each sub-image. Using receiver operating characteristic analysis, we show that the proposed metric more accurately reflects such ability than Moran's metric. Incorporating the proposed metric into a hierarchical non-rigid registration scheme, we show that registration accuracy is improved relative to Moran's metric. |
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Keywords: | Non-rigid registration Locally affine transformation Hierarchical elastic registration |
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