Nano-CdZr4(PO4)6 as a reusable and robust catalyst for the synthesis of bis-thiazolidinones by a multicomponent reaction of aldehydes,ethylenediamine and thioglycolic acid |
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Authors: | Javad Safaei-Ghomi Seyed Hadi Nazemzadeh Hossein Shahbazi-Alavi |
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Affiliation: | 1. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran;2. Young Researchers and Elite Club, Kashan Branch, Islamic Azad University, Kashan, Iran |
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Abstract: | Nano-CdZr4(PO4)6 has been used as an efficient catalyst for the preparation of bis-thiazolidinones by pseudo-five-component reaction of aldehydes, ethylenediamine and thioglycolic acid under reflux conditions in toluene. The present synthetic protocol has several advantages, such as simplicity, excellent yields, short reaction times, reusability of the catalyst and low catalyst loading. |
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Keywords: | Bis-thiazolidinones nano-CdZr4(PO4)6 ethylenediamine catalytic activity one-pot reaction |
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