Limb development: marginal fringe benefits |
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Authors: | SS Blair |
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Affiliation: | Department of Zoology, 250 N. Mills St., University of Wisconsin, Madison 53706, USA. |
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Abstract: | Recent results show that in the developing Drosophila wing, the secreted pioneer protein Fringe regulates the sensitivity of the Notch signaling pathway to different ligands. This provides a likely mechanism by which Fringe-like molecules may control patterning in both Drosophila and vertebrates. |
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