Electrochemistry assisted reacting deposition of hydroxyapatite in porous chitosan scaffolds

Electrochemistry assisted reacting deposition method was employed to prepare porous chitosan/hydroxyapatite (CS/HA) composite scaffold with a new design device using ion exchange membranes to separate calcium salt and phosphate solutions. The results determined from XRD and SEM indicates hydroxyapatite can be electrochemically deposited in the chitosan scaffold using the device. After electrochemistry assisted reacting deposition, the surface of the chitosan scaffold was coated with low crystalline HA, particularly at the frame edge of the scaffold. The pores in the scaffold still kept interconnected well and the deposited hydroxyapatite has a cluster microsphere shape whose size is about 3-5 μm.