对本院258例药品不良反应的回顾性分析

目的: 加强对药品不良反应(ADR)监测,提倡合理用药,降低ADR发生率。方法: 对本院五年来收集的258例ADR报告进行统计和分析。结果: ADR上报总数偏少,特别是护理人员上报ADR的数量仅占8.92%。在258例ADR报告中,21～80岁年龄段ADR发生率较高,占8.98%～22.09%;不同给药途径,静脉滴注给药的ADR发生率最高,占67.05%;累及各系统ADR以对皮肤及附属器官损害发生率最高,占41.08%;在引发ADR的各类药品中,抗菌药物引发的ADR最多,占42.64%。结论: 药物不合理应用可使ADR发生率上升。

Retrospective analysis of the 258 adxerse drug reaction cases in our hospital

AIM: To strengthen the monitoring of adverse drug reaction (ADR), and promote rational drug use and decrease the incidence rate of ADR.METHODS: 258 ADR case reports were collected and analyzed in our hospital in recent 5 years.RESULTS: The number of the reports about ADR was less, especially the number of ADR reported by nursing staff, which only accounting for 8.92% among total cases. In 258 cases of ADR reports, the higher incidence rate of ADR occured in the age of 21 to 80, which accounting for 8.98%-22.09%.In the different routes of administration, intravenous drip had the highest incidence rate, which was about 67.05%.Skin and accessory organs diseases were involved in ADR, and the incidence rate of ADR was highest, accounting for 41.08%.In various kinds of drugs in ADR, the antibacterials raising the incidence rate of ADR was highest, accounting for 42.64%.CONCLUSION: Unreasonable drug application will increase ADR incidence.