MIC反应器处理抗生素发酵废液的研究

采用逐步提高抗生素浓度和有机负荷(OLR)的方法,考察改进型内循环厌氧反应器(MIC反应器)对含万古霉素(VA)发酵废液的处理效果,并对微生物群落进行分析。结果表明,污泥经过驯化后,MIC反应器对VA发酵废液有较好的处理能力,当进水VA浓度为70 mg/L左右、水力停留时间(HRT)为4 d时,对MIC反应器运行没有抑制效应,此时COD去除率约为90%,VA去除率达到90%以上;当HRT为2 d、进水OLR为25 kgCOD/(m^3·d)时,MIC反应器对VA发酵废液的COD去除负荷最大,为19.5 kg/(m^3·d)。通过微生物多样性检测结果发现,细菌群落在门水平上的优势菌为Bacteroidetes和Firmicutes。

Treatment of Antibiotic Fermentation Waste Liquid by MIC Reactor

By gradually increasing antibiotics concentration and organic loading rate (OLR),the treatment efficiency of modified internal circulation anaerobic reactor (MIC reactor) on the vancomycin (VA)-containing antibiotic fermentation waste liquid was investigated,and the microbial community was analyzed. The MIC reactor had good performance for the treatment of VA-containing fermentation waste liquid after the domestication of the sludge. When the influent VA concentration was about 70 mg/L and hydraulic retention time (HRT) was 4 days,no inhibitory effect on the operation of the MIC reactor was observed. At this time,the COD removal rate was about 90% and the VA removal rate was over 90%.When HRT was 2 days and OLR was 25 kgCOD/ (m^3·d),the maximum COD removal loading of VAcontaining fermentation waste liquid was achieved by the MIC reactor,which was 19. 5 kg/ (m^3·d).The result of microbial diversity analysis showed that Bacteroidetes and Firmicutes were the dominant bacteria at the phylum level.