Modification of silica gel,cellulose, and polyurethane with a sterically hindered N‐halamine moiety to produce antimicrobial activity |
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Authors: | K. Barnes J. Liang S. D. Worley J. Lee R. M. Broughton T. S. Huang |
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Affiliation: | 1. Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849;2. Department of Polymer and Fiber Engineering, Auburn University, Auburn, Alabama 36849;3. Department of Nutrition and Food Science, Auburn University, Auburn, Alabama 36849 |
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Abstract: | The sterically hindered amine monomer 4‐[3‐triethoxysilylpropoxyl]‐2,2,6,6‐tetramethylpiperidine has been synthesized and covalently bonded to the surfaces of silica gel particles and cellulose (cotton) and copolymerized in a polyurethane coating formulation. Upon exposure to dilute sodium hypochlorite (household bleach), a very stable N‐Cl bond is formed in situ at the hindered amine nitrogen site. This source of oxidative chlorine provides an antimicrobial function to the silica gel, cotton, and polyurethane. Stability, regenerability, and biocidal efficacy data are presented. The new N‐halamine materials were remarkably effective against Staphylococcus aureus and Escherichia coli O157 : H7 in brief periods of contact. The materials should find application in water treatment and medical applications. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007 |
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Keywords: | biofibers biological applications of polymers biomaterials biopolymers functionalization of polymers |
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