Behavior of α‐ and β‐cyclodextrin‐encapsulated allyl isothiocyanate as slow‐release additives in polylactide‐co‐polycaprolactone films |
| |
Authors: | David Plackett Afshin Ghanbari‐Siahkali Lajos Szente |
| |
Affiliation: | 1. The Danish Polymer Centre, Ris? National Laboratory, Frederiksborgvej 399, DK‐4000 Roskilde, Denmark;2. NKT Flexibles I/S, Priorparken 510, 2605 Br?ndby, Denmark;3. Cyclolab, Cyclodextrin Research and Development Laboratory, H‐1525 Budapest, Hungary |
| |
Abstract: | The natural antibacterial agent allyl isothiocyanate (AITC) encapsulated in either α‐ or β‐cyclodextrin (CD) has previously been evaluated as a slow‐release additive in polylactide‐co‐polycaprolactone (PLA–PCL) films designed for use in cheese packaging. In the research described in this article, thermogravimetric analysis (TGA) and thermogravimetric analysis in tandem with mass spectrometry (TGA–MS) were used to explore the thermal properties of CD‐encapsulated AITC complexes as well as those of PLA–PCL films containing these complexes. To our knowledge, this is the first reported application of the TGA–MS technique to explore the thermal stability of CD‐entrapped AITC and the first study to report differences in thermal stability of AITC in α‐and β‐CD cavities in the solid state. Observed differences in the thermal degradation profile of films containing the CD complexes can be explained if AITC binds more strongly to β‐CD than to α‐CD. This hypothesis has been reinforced by gas chromatography (GC) and high performance liquid chromatography (HPLC) studies, the results of which suggest that a new covalently bound AITC–CD complex may be formed when incorporating the β‐CD complex of AITC in PLA–PCL films but not when incorporating the α‐CD complex of AITC. This finding means that the α‐CD complex of AITC would be preferred in situations where adequate long‐term controlled release of AITC from polymer films is required, as for example in the case of active packaging applications. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007 |
| |
Keywords: | cyclodextrins allyl isothiocyanate slow‐release additives biopolymer packaging polylactide‐co‐polycaprolactone |
|
|