Preparation of porous chitosan/agarose microsphere and its R‐phycoerythrin release properties |
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| Authors: | Zhi‐Xin Xue Gui‐Peng Yang Guang‐Ce Wang Jian‐Feng Niu Xiao‐Yan Cao |
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| Affiliation: | 1. Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, Qingdao 266003, People's Republic of China;2. College of Chemical Engineering, Qingdao University, Qingdao 266071, People's Republic of China;3. Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, People's Republic of China;4. Tianjin University of Technology and Science, Tianjin 300071, People's Republic of China;5. Graduate School, The Chinese Academy of Science, Beijing 100039, People's Republic of China |
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| Abstract: | The chitosan microspheres (CS‐CL) were prepared by suspension crosslinking method and used as carriers of R‐phycoerythrin (R‐PE). In this study, R‐PE was loaded in the microspheres and released in vitro. The effects of pH value, temperature, ionic strength, and R‐PE concentration on loading efficiency and release behavior were discussed. A novel microsphere that contained agarose (CS‐AR MP) was prepared and the basic loading and releasing behavior for R‐PE of this kind of new microspheres were also investigated. The results showed that all these chitosan microspheres have the ability to control‐release R‐PE. The addition of agarose may somewhat accelerate the release rate of R‐PE from microspheres and reduce the capacity of adsorption for R‐PE. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 103: 2759–2766, 2007 |
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| Keywords: | chitosan microspheres R‐phycoerythrin control‐release agarose |
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