Preparation and antibacterial activity of PET/chitosan nanofibrous mats using an electrospinning technique |
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| Authors: | Kyung‐Hye Jung Man‐Woo Huh Wan Meng Jiang Yuan Seok Hee Hyun Jung‐Sook Bae Samuel M Hudson Inn‐Kyu Kang |
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| Affiliation: | 1. Department of Polymer Science, Kyungpook National University, Daegu, Korea;2. School of Textiles and Fashion Technology, Kyungil University, Kyungsan, Korea;3. Center for Scientific Instruments, Kyungpook National University, Daegu, Korea;4. Department of Fashion Design, Daegu University, Kyungsan, Korea;5. Chemistry and Science Department, Textile Engineering, College of Textiles, NC State University, Raleigh, NC |
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| Abstract: | The nanofiber deposition method, by electrospinning, was employed to introduce antibacterial activity and biocompatibility to the surface of poly (ethylene terephthalate) (PET) textiles. The polymer blends of PET and chitosan were electrospun on to the PET micro‐nonwoven mats for biomedical applications. The PET/chitosan nanofibers were evenly deposited on to the surface, and the diameter of the nanofibers was in the range between 500 and 800 nm. The surface of the nanofibers was characterized using SEM, ESCA, AFM, and ATR‐FTIR. The wettability of the PET nanofibers was significantly enhanced by the incorporation of chitosan. The antibacterial activity of the samples was evaluated utilizing the colony counting method against Staphylococcus aureus and Klebsiella pneumoniae. The results indicated that the PET/chitosan nanofiber mats showed a significantly higher growth inhibition rate compared with the PET nanofiber control. In addition, the fibroblast cells adhered better to the PET/chitosan nanofibers than to the PET nanofibers mats, suggesting better tissue compatibility. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007 |
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| Keywords: | nanofiber polyester chitosan antibacterial activity |
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