Mechanisms of action of inhaled fibers, particles and nanoparticles in lung and cardiovascular diseases |
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| Authors: | Brooke T Mossman Paul J Borm Vincent Castranova Daniel L Costa Kenneth Donaldson and Steven R Kleeberger |
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| Affiliation: | (1) Department of Pathology, University of Vermont, 89 Beaumont Avenue, HSRF 218, Burlington, VT 05405, USA;(2) University of Heerlen, CEL, Nieuw Eyckholt 300, Heerlen, 6400 AN, The Netherlands;(3) National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Pathology and Physiology Research Branch, 1095 Willowdale Road, Morgantown, WV 26505, USA;(4) Environmental Protection Agency, E205-09, EPA/ORD, Research Triangle Park, NC 27711, USA;(5) Queen's Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK;(6) National Institute of Environmental Health Sciences, MD D2-01, P. O. Box 12233, Research Triangle Park, NC 27709, USA |
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| Abstract: | Background A symposium on the mechanisms of action of inhaled airborne particulate matter (PM), pathogenic particles and fibers such
as silica and asbestos, and nanomaterials, defined as synthetic particles or fibers less than 100 nm in diameter, was held
on October 27 and 28, 2005, at the Environmental Protection Agency (EPA) Conference Center in Research Triangle Park, North
Carolina. The meeting was the eighth in a series of transatlantic conferences first held in Penarth, Wales, at the Medical
Research Council Pneumoconiosis Unit (1979), that have fostered long-standing collaborations between researchers in the fields
of mineralogy, cell and molecular biology, pathology, toxicology, and environmental/occupational health. |
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