Transport of dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine |
| |
Authors: | CL Martel JB Mackic JD Adams JG McComb MH Weiss BV Zlokovic |
| |
Affiliation: | College of Veterinary Medicine, Oregon State University, Corvallis 97331, USA. |
| |
Abstract: | Diagnostic procedures for detection of infectious laryngotracheitis virus in tracheas of experimentally infected chickens, including the indirect fluorescent antibody test (IFAT), immunoperoxidase (IP), virus isolation (VI), histopathology, polymerase chain reaction (PCR), and DNA hybridization, were performed and compared. Using VI as a reference, we calculated the sensitivity and specificity of the tests. The sensitivities of IP, IFAT, histopathology, PCR, and hybridization were 100%, 93%, 7%, 27%, and 0%, respectively, and the specificities of IP, IFAT, histopathology, PCR, and hybridization were 93%, 93%, 100%, 100%, and 100%, respectively. Histopathology, PCR, and hybridization were more specific but lacked sensitivity compared to IP and IFAT. IP and IFAT were equally specific, but IP was more sensitive than IFAT. Based on these results, IP performed better than any other test. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|