p-Chloroacetophenone: A study of enolization kinetics |
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| Authors: | Swati Malhotra Dipika Jaspal |
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| Affiliation: | 1. Department of Research and P.G. Studies in Chemistry, Govt., SLP College, Gwalior, Madhya Pradesh, India;2. Department of Applied Science, Symbiosis Institute of Technology, A constituent of Symbiosis International University, Pune, Maharashtra, India |
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| Abstract: | The reaction rate of enolization of p-chloroacetophenone has been studied in the presence of amino acids, namely, β-alanine, DL-alanine, L-alanine, and glycine. Maximum reaction rate was observed in the case of β-alanine at 22M concentration. The effects of parameters such as effect of ketone concentration, effect of dielectric constant, effect of catalysts, etc., have been found to exert a significant effect on the reaction rate. The effect of temperature was studied in the range of 313–328?K, and several thermodynamic parameters such as entropy (ΔS≠), enthalpy (ΔH≠), energy of activation (ΔEa), and Gibbs free energy (ΔF≠) were found to be ?10.32?e.u., 17.87?cal?mol?1, 19.24?kcal?mol?1, and 21.20?cal?mol?1, respectively. The reaction rate increased from 1.9 to 5.8?min?1 on increasing the percentage of dimethylformamide from 10 to 50% (v/v). |
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| Keywords: | Amino acids catalysis enolization kinetics p-Chloroacetophenone thermodynamics |
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