Rasmussen's encephalitis: an autoimmune disorder? |
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Authors: | PI Andrews JO McNamara |
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Affiliation: | Duke Center for the Advanced Study of Epilepsy, Duke University Medical Center, Durham, North Carolina 27710, USA. |
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Abstract: | Rasmussen's encephalitis is a rare progressive pediatric epileptic syndrome. Recent evidence from experimental animals and patients with the disease suggests an important role for both humoral and cell-mediated immune mechanisms in the pathogenesis of this disease. The glutamate receptor subunit GluR3 may be an important autoantigen in the disease. (This review has been modified from a review published in Current Opinion in Neurology 1996, 9:141-145.) |
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