| 淀粉与聚乳酸接枝共聚物的制备与表征 |
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| 引用本文： | 谢德明,施云峰,谢春兰,周长忍.淀粉与聚乳酸接枝共聚物的制备与表征[J].材料科学与工程学报,2006,24(6):835-838. |
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| 作者姓名： | 谢德明 施云峰 谢春兰 周长忍 |
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| 作者单位： | 1. 暨南大学生物医学工程系,广东,广州,510632
2. 暨南大学材料科学与工程系,广东,广州,510632 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 采用三甲基硅烷基(TMS)保护淀粉作为大分子引发剂,辛酸亚锡催化,制备聚乳酸与淀粉的接枝共聚物.红外光谱和核磁共振氢谱分析证实了共聚物的形成.接触角测试结果表明亲水性糖基的引入使共聚物具有较好的亲水性.在pH=7.2的PBS缓冲液中,共聚物膜能较快降解,6d后失重率接近50%,10d后完全降解.对聚乳酸进行糖基化改性,将大大拓展聚乳酸类材料在生物医学领域的应用范围.
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| 关 键 词： | 聚乳酸 淀粉 接枝共聚 生物材料 |
| 文章编号： | 1673-2812(2006)06-0835-04 |
| 修稿时间： | 2006年2月6日 |
Preparation and Characterization of Starch-polylactide Copolymers |
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| XIE De-ming,SHI Yun-feng,XIE Chun-lan,ZHOU Chang-ren.Preparation and Characterization of Starch-polylactide Copolymers[J].Journal of Materials Science and Engineering,2006,24(6):835-838. |
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| Authors: | XIE De-ming SHI Yun-feng XIE Chun-lan ZHOU Chang-ren |
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| Abstract: | Polylactide(PLA)-grafted starch copolymers were synthesized successfully by a bulk polymerization reaction using the trimethylsilyl-protected(TMS) starch as macroinitiator and stannous octoate as catalyst when starch was degraded previously.FT-IR and()~1H NMR were used to characterize the copolymer molecular structure.The results of contact angle determination showed that PLA-starch copolymer were more hydrophilic than pure PLA because of the introduction of glycosyl.The copolymer films degraded in higher rate than PLA in the PBS solution which pH=7.2,its weight loss percent reached nearly 50% after 6 days and degraded completely after 10 days.The results demonstrate that glycosylation PLA polymeric materials would have more potential in biomedical application than PLA. |
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| Keywords: | polylactide starch graft copolymer biomaterials |
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