An object-oriented database for protein structure analysis |
| |
Authors: | Gray, Peter M.D. Paton, Norman W. Kemp, Graham J.L. Fothergill, John E. |
| |
Affiliation: | 1Departments of Computing Science, University of Aberdeen, King's College Aberdeen, UK 2Department of Biochemistry, University of Aberdeen, King's College Aberdeen, UK |
| |
Abstract: | An object-oriented database system has been developed whichis being used to store protein structure data. The databasecan be queried using the logic programming language Prolog orthe query language Daplex. Queries retrieve information by navigatingthrough a network of objects which represent the primary, secondaryand tertiary structures of proteins. Routines written in bothProlog and Daplex can integrate complex calculations with theretrieval of data from the database, and can also be storedin the database for sharing among users. Thus object-orienteddatabases are better suited to prototyping applications andanswering complex queries about protein structure than relationaldatabases. This system has been used to find loops of varyinglength and anchor positions when modelling homologous proteinstructures. |
| |
Keywords: | database/ object-oriented/ protein modelling/ protein structure/ prototyping |
本文献已被 Oxford 等数据库收录! |
|