Study of the geometry in a 3D flow-focusing device |
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Authors: | Elena Castro-Hernández Maarten P Kok Michel Versluis David Fernandez Rivas |
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Affiliation: | 1.área de Mecánica de Fluidos, Departamento de Ingeniería Aeroespacial y Mecánica de Fluidos,Universidad de Sevilla,Seville,Spain;2.Physics of Fluids Group,MESA+ Institute of Nanotechnology, University of Twente,Enschede,The Netherlands;3.Mesoscale Chemical Systems,MESA+ Institute of Nanotechnology, University of Twente,Enschede,The Netherlands |
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Abstract: | We present a numerical and experimental study on a non-planar three-dimensional design of a microfluidic flow-focusing device for the well-controlled generation of monodisperse micron-sized droplets. Three relevant geometric parameters were identified: the distance between the inner inlet channel and the outlet channel, the width of the outlet channel, and its length. Simulation data extracted from a full parameter study and finite element simulations yielded four optimum designs that were then fabricated using soft lithography techniques. Under the predicted operating conditions, micro-droplets of a size of \({\sim}1\,\upmu \text {m}\) in diameter are obtained from a channel \(50\,\upmu \text {m}\) in width. This work represents an important breakthrough in the practical use of flow-focusing devices delivering a ratio of constriction to droplet size of 50 times, with the advantage of reduced clogging of the micro-channel, greatly improving the control and reliability of the device. |
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