Study of factors affecting the determination of total plasma 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate (SBD)-thiol derivatives by liquid chromatography |
| |
Authors: | V Rizzo L Montalbetti M Valli T Bosoni E Scoglio R Moratti |
| |
Affiliation: | Camelracing Forensic Laboratory, Forensic Science Laboratory, Abu Dhabi, United Arab Emirates. |
| |
Abstract: | A flunixin metabolite, a hydroxylated product, has been identified in camel urine and plasma samples using gas chromatography-mass spectrometry (GC-MS) and GC-MS-MS in the electron impact and chemical ionization modes. Its major fragmentation pattern has been verified by GC-MS-MS in daughter ion and parent ion scan modes. The method could detect flunixin and its metabolite in camel urine after a single intravenous dose of 2.2 mg of flunixin/kg body weight for 96 and 48 h, respectively, which increases the reliability of antidoping control analysis. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|